反应详情

To a solution of compound 399 (316.1 mg, 1214 μmol) in ethanol (15 mL) was added palladium hydroxide, 20 wt % pd (dry basis) on carbon, wet (300 mg, 427 μmol). After hydrogenating the reaction mixture at 50 psi for 6 days, the mixture was filtered thru a plug of celite and concentrated in vacuo to give compound 400 (287.0 mg). LCMS-ESI (POS), M/Z, M+1: Found 171.1, Calculated 171.1.

1. dry with materialpalladium hydroxide, 20 wt % pd (dry basis) on carbon, wet (300 mg, 427 μmol)
2. customfor 6 days
3. filtrationthe mixture was filtered
4. concentrationconcentrated in vacuo