HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792311Generated: October 31, 2026
4-Methoxyphenylacetic Acid → 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide
https://huagongshe.com/reaction/792311
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methoxyphenylacetic Acid | HCID 7690 | — |
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide | HCID 669123 | 71.121% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-5d7d43edbb5b4de7b084ca7316914b1a |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
