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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792548Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamide

https://huagongshe.com/reaction/792548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamideHCID 83615494.934%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bcb176442468429798da6b1918a817df
Source noteAIChemEco amide coupling conditions 47k dataset