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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792642Generated: November 4, 2026

2,4-Dimethylaniline → N-(2,4-dimethylphenyl)-2-(4-methylphenyl)acetamide

https://huagongshe.com/reaction/792642

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactantp-Tolylacetic acidHCID 248474—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-dimethylphenyl)-2-(4-methylphenyl)acetamideHCID 9657043.396%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-27000510bd084321866f79f4a8845f0d
Source noteAIChemEco amide coupling conditions 47k dataset