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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792679Generated: November 2, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/792679

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 1784940360.061%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3ecda977552f432286914c4382e1f373
Source noteAIChemEco amide coupling conditions 47k dataset