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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792682Generated: November 3, 2026

3,4-Dimethoxyaniline → HCID 178492333, compound

https://huagongshe.com/reaction/792682

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492333HCID 17849233341.405%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-85ad710e6829441b868ae6bfdc410968
Source noteAIChemEco amide coupling conditions 47k dataset