Hydrochloric Acid → HCID 67259420, compound

Participants

Reaction Steps

To a solution of tert-butyl 3-(6-((3-ethyl-4-(imidazo[1,2-a]pyridine-3-carboxamido)-1H-indazol-1-yl)methyl)pyridin-2-yloxy)propylcarbamate (17.2 mg, 0.0302 mmol) in ethyl acetate was added hydrogen chloride (1 mL; 4M in dioxane). The mixture was stirred for 30 minutes. The solvent was removed under reduced pressure to give N-(1-((6-(3-aminopropoxy)pyridin-2-yl)methyl)-3-ethyl-1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide dihydrochloride (11.6 mg). MS (APCI), positive scan, m/z=470.1 (M+H).

Provenance & Evidence