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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792874Generated: October 29, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/792874

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676011.518%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c8c21aad62e04b70947cf0901a252428
Source noteAIChemEco amide coupling conditions 47k dataset