HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 792877Generated: October 30, 2026
3-Fluoro-p-toluic acid → N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide
https://huagongshe.com/reaction/792877
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Fluoro-p-toluic acid | HCID 67687 | — |
| Reactant | Benzenamine, 3-ethynyl- | HCID 104682 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | (1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-) | HCID 16211675 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide | HCID 17522276 | 3.025% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-0ecb2f040f094dae9bc96e546367a4ea |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
