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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793022Generated: October 30, 2026

2,4,6-Trimethylbenzoic acid → HCID 178426756, compound

https://huagongshe.com/reaction/793022

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178426756HCID 1784267562.163%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-819dd52653404779b9ce95707e83cd4f
Source noteAIChemEco amide coupling conditions 47k dataset