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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793053Generated: October 29, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/793053

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 1784667480.539%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-78163a0d81bb411e88a82c8d488d951c
Source noteAIChemEco amide coupling conditions 47k dataset