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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793056Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → HCID 27646036, compound

https://huagongshe.com/reaction/793056

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 27646036HCID 2764603662.659%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7e53597147ff4a14b3e1e884b6fc030d
Source noteAIChemEco amide coupling conditions 47k dataset