Trifluoroacetic acid → N-(3-ethyl-1-((6-(piperidin-4-yloxy)pyridin-2-yl)methyl)-1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide

Participants

Reaction Steps

To tert-butyl 4-(6-((3-ethyl-4-(imidazo[1,2-a]pyridine-3-carboxamido)-1H-indazol-1-yl)methyl)pyridin-2-yloxy)piperidine-1-carboxylate (3 mg, 0.02 mmol) in DCM (1 mL) was added TFA (1 mL). The reaction mixture was stirred for one hour and concentrated. Silica gel chromatography of the crude material (DCM/MeOH/NH4OH 10:1:0.1) provided the desired product (2 mg). MS (ES+APCI) m/z=496 (M+H).

Provenance & Evidence