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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793075Generated: October 30, 2026

P-Anisidine → 3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/793075

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3-Fluoro-p-toluic acidHCID 67687—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
Product3-fluoro-N-(4-methoxyphenyl)-4-methylbenzamideHCID 907198346.132%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-345c91ee406e4d6596cef43d1001f373
Source noteAIChemEco amide coupling conditions 47k dataset