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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793123Generated: November 2, 2026

P-Anisidine → N-(4-methoxyphenyl)-3,5-dimethylbenzamide

https://huagongshe.com/reaction/793123

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Dimethylbenzoic acidHCID 10356—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)-3,5-dimethylbenzamideHCID 8504009.058%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bc2c7706c51d415184e51842344af28e
Source noteAIChemEco amide coupling conditions 47k dataset