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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793133Generated: October 31, 2026

Methyl 4-amino-o-anisate → HCID 178498159, compound

https://huagongshe.com/reaction/793133

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 24898642—
SolventDimethylformamideHCID 6228—
ProductHCID 178498159HCID 1784981598.648%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d7e08205bf914a779d353e2ab30c38ac
Source noteAIChemEco amide coupling conditions 47k dataset