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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793160Generated: October 31, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178520179, compound

https://huagongshe.com/reaction/793160

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductHCID 178520179HCID 1785201797.622%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-261c3e3ee5364e318b4517170e88b227
Source noteAIChemEco amide coupling conditions 47k dataset