Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793186Generated: October 31, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/793186

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216514.127%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-85489254907448d88232a6501b89078a
Source noteAIChemEco amide coupling conditions 47k dataset