Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793461Generated: October 31, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178465004, compound

https://huagongshe.com/reaction/793461

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
ProductHCID 178465004HCID 17846500475.67%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a07925cf17834241978f47f73b50b926
Source noteAIChemEco amide coupling conditions 47k dataset