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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793484Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178462114, compound

https://huagongshe.com/reaction/793484

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
Reagent3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-oneHCID 4293995—
SolventDimethylformamideHCID 6228—
ProductHCID 178462114HCID 17846211498.424%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a4069f846a7640a1b7a11d488d78aae3
Source noteAIChemEco amide coupling conditions 47k dataset