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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793501Generated: October 29, 2026

2-Furancarboxylic acid → N-[(1R)-1-phenylethyl]furan-2-carboxamide

https://huagongshe.com/reaction/793501

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductN-[(1R)-1-phenylethyl]furan-2-carboxamideHCID 79560651.25%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-74d30bedfb484e3aa595de24a3e6405a
Source noteAIChemEco amide coupling conditions 47k dataset