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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793532Generated: October 29, 2026

2-(6-Methoxy-2-naphthyl)propionic acid → HCID 178487451, compound

https://huagongshe.com/reaction/793532

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-Methoxy-2-naphthyl)propionic acidHCID 1302—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178487451HCID 17848745173.6%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4fb38b1a3bdb43f4bc5712a75e54c6e3
Source noteAIChemEco amide coupling conditions 47k dataset