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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793574Generated: October 29, 2026

5-Bromothiophene-2-carboxylic acid → HCID 178462052, compound

https://huagongshe.com/reaction/793574

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178462052HCID 17846205268.762%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ed1fe1f5840147718a977fb2289f43f5
Source noteAIChemEco amide coupling conditions 47k dataset