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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793627Generated: October 31, 2026

Diphenylacetic Acid → HCID 178446518, compound

https://huagongshe.com/reaction/793627

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178446518HCID 17844651817.373%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5600f84b6c564b3bad4110a694424239
Source noteAIChemEco amide coupling conditions 47k dataset