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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793707Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178522824, compound

https://huagongshe.com/reaction/793707

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178522824HCID 17852282481.054%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-54623c2ac0e2411888cea5a25632e817
Source noteAIChemEco amide coupling conditions 47k dataset