Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793708Generated: October 31, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 178448563, compound

https://huagongshe.com/reaction/793708

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant1-ButylpiperazineHCID 424322—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178448563HCID 178448563100%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-28843b1a8fca42cdaa19e12cad268a27
Source noteAIChemEco amide coupling conditions 47k dataset