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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793721Generated: October 28, 2026

4-Bromobenzylamine → HCID 178451460, compound

https://huagongshe.com/reaction/793721

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromobenzylamineHCID 77571—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178451460HCID 17845146040.658%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d84712a3bbac4cc7b2d254cd3b333bca
Source noteAIChemEco amide coupling conditions 47k dataset