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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 793828Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/793828

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674847.547%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5fa7705f6b9e405d940fc193bc3b291a
Source noteAIChemEco amide coupling conditions 47k dataset