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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7939Generated: October 27, 2026

2-isobutyl-4-methoxycarbonyl-6-(4-methylphenyl)-2H-pyridazin-3-one → 4-carboxy-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-one

https://huagongshe.com/reaction/7939

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-isobutyl-4-methoxycarbonyl-6-(4-methylphenyl)-2H-pyridazin-3-oneHCID 21991442—
Reactant4-carboxy-6-(3-fluoro-4-methylphenyl)-2-isobutyl-2H-pyridazin-3-oneHCID 21991481—
Product4-carboxy-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-oneHCID 21991635—

Reaction Steps

Following the procedure of Example 1 (7), 2-isobutyl-4-methoxycarbonyl-6-(4-methylphenyl)-2H-pyridazin-3-one was reacted to yield the title compound as slightly yellow needles (yield: 86.7%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-8a650fee2ff8484493b5687f5a40859d
Source noteuspto-grants-2006_08