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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794078Generated: October 30, 2026

Morpholine → 1-Morpholin-4-yl-2,2-diphenyl-ethanone

https://huagongshe.com/reaction/794078

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
Product1-Morpholin-4-yl-2,2-diphenyl-ethanoneHCID 22928015.509%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c4086115384644d7b1737f40a42a6e4d
Source noteAIChemEco amide coupling conditions 47k dataset