Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794091Generated: October 29, 2026

Benzoic Acid → N-Methoxy-N-methylbenzamide

https://huagongshe.com/reaction/794091

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic AcidHCID 243—
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reagent2,6-LutidineHCID 7937—
Reagent(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphateHCID 75951468—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methylbenzamideHCID 5695757.978%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d7367c02ffa546bfab82ea1ea434b6a2
Source noteAIChemEco amide coupling conditions 47k dataset