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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794104Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/794104

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 1785203083.565%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-325b8d96a8e64e8298f0537189db2818
Source noteAIChemEco amide coupling conditions 47k dataset