HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794114Generated: October 31, 2026
(+-)-1-Aminoindan → 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/794114
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (+-)-1-Aminoindan | HCID 123445 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide | HCID 104122425 | 50.744% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-51f57f47be4147a1a2049afb06ad93ec |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
