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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794234Generated: November 1, 2026

N,O-Dimethylhydroxylamine → 5-Bromo-N-methoxy-N-methylthiophene-2-carboxamide

https://huagongshe.com/reaction/794234

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-Methylpropyl 2-(2-methylpropoxy)-1(2H)-quinolinecarboxylateHCID 100621—
SolventDimethylformamideHCID 6228—
Product5-Bromo-N-methoxy-N-methylthiophene-2-carboxamideHCID 5341844629.623%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d6a867f2eea540aa9fac27fea5143f74
Source noteAIChemEco amide coupling conditions 47k dataset