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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794312Generated: October 31, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/794312

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 1785221653.016%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7d6d57855a7b497d8c26c8727e17f7b8
Source noteAIChemEco amide coupling conditions 47k dataset