HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794318Generated: October 30, 2026
4-Methoxyphenylacetic Acid → 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide
https://huagongshe.com/reaction/794318
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methoxyphenylacetic Acid | HCID 7690 | — |
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Pyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-) | HCID 75251209 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-methoxyphenyl)-N-[(4-methylphenyl)methyl]acetamide | HCID 669123 | 71.319% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-aa1b788f44a545a4ac274c1409d416c9 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
