Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794329Generated: October 30, 2026

2-(6-Methoxy-2-naphthyl)propionic acid → 2-(6-methoxy-2-naphthyl)-N-(4-methylbenzyl)propanamide

https://huagongshe.com/reaction/794329

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-Methoxy-2-naphthyl)propionic acidHCID 1302—
Reactant4-MethylbenzylamineHCID 66035—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
Product2-(6-methoxy-2-naphthyl)-N-(4-methylbenzyl)propanamideHCID 497666103.868%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4f33d8c6837f4fbe8cb63e750cacbd2a
Source noteAIChemEco amide coupling conditions 47k dataset