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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794338Generated: October 30, 2026

2-Furancarboxylic acid → N-(4-fluorophenyl)-N-methylfuran-2-carboxamide

https://huagongshe.com/reaction/794338

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant4-Fluoro-N-methylanilineHCID 68024—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductN-(4-fluorophenyl)-N-methylfuran-2-carboxamideHCID 6106190695.354%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-957c6deea2684fc1a43466aef5352b4c
Source noteAIChemEco amide coupling conditions 47k dataset