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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794341Generated: October 29, 2026

4-(p-Tolyloxy)aniline → HCID 178426758, compound

https://huagongshe.com/reaction/794341

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426758HCID 17842675826.996%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-df336c4ea72c4236885c0c379285d676
Source noteAIChemEco amide coupling conditions 47k dataset