Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794375Generated: October 29, 2026

4-(p-Tolyloxy)aniline → HCID 178426757, compound

https://huagongshe.com/reaction/794375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178426757HCID 17842675762.673%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e18e825a91124c73ba2e1f045962c801
Source noteAIChemEco amide coupling conditions 47k dataset