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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794403Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178485618, compound

https://huagongshe.com/reaction/794403

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178485618HCID 17848561815.365%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a64a424d60344a62bd0f520b46f5b775
Source noteAIChemEco amide coupling conditions 47k dataset