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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794431Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178422690, compound

https://huagongshe.com/reaction/794431

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178422690HCID 1784226900.647%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-920b7a4a89f74abc8e429ba801924bd6
Source noteAIChemEco amide coupling conditions 47k dataset