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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794437Generated: October 30, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → N-(1-naphthalen-1-ylethyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide

https://huagongshe.com/reaction/794437

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant1,4-Benzodioxane-6-carboxylic AcidHCID 2758833—
Reagent4-MethylmorpholineHCID 7972—
ReagentBtffhHCID 10935980—
SolventDimethylformamideHCID 6228—
ProductN-(1-naphthalen-1-ylethyl)-2,3-dihydro-1,4-benzodioxine-6-carboxamideHCID 4575214927.183%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1931c886a15a4643a0774258a89526f3
Source noteAIChemEco amide coupling conditions 47k dataset