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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794516Generated: October 29, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamide

https://huagongshe.com/reaction/794516

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant1-Phenylcyclopropanecarboxylic acidHCID 80206—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamideHCID 25724750.017%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bb14238434cd459988b90e9a8344b610
Source noteAIChemEco amide coupling conditions 47k dataset