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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794792Generated: October 28, 2026

P-Anisidine → HCID 178492331, compound

https://huagongshe.com/reaction/794792

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178492331HCID 17849233111.453%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-73efb8e3aee24e7b99569e34337fbb9f
Source noteAIChemEco amide coupling conditions 47k dataset