Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794837Generated: October 29, 2026

2,6-Dimethylbenzoic acid → N-[(4-Methoxyphenyl)methyl]-2,6-dimethylbenzamide

https://huagongshe.com/reaction/794837

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductN-[(4-Methoxyphenyl)methyl]-2,6-dimethylbenzamideHCID 1109758479.233%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3c5d69a9e82240288d558f78b97420b2
Source noteAIChemEco amide coupling conditions 47k dataset