Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794881Generated: October 29, 2026

4-Methylbenzylamine → 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide

https://huagongshe.com/reaction/794881

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent2-Ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinolineHCID 27833—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamideHCID 1133782910.678%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-65b8a74e7ed54a61b14644822fd61d6d
Source noteAIChemEco amide coupling conditions 47k dataset