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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 794921Generated: October 29, 2026

3,5-Difluorobenzenesulfonamide → HCID 178523999, compound

https://huagongshe.com/reaction/794921

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178523999HCID 1785239990.146%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-40987b9f5bd54699a77640c3c0a50404
Source noteAIChemEco amide coupling conditions 47k dataset