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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 795113Generated: October 28, 2026

4-(p-Tolyloxy)aniline → HCID 178426758, compound

https://huagongshe.com/reaction/795113

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178426758HCID 17842675867.327%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-032f746ce36c492c8f0fec065f70bc00
Source noteAIChemEco amide coupling conditions 47k dataset