HCID 21991423, compound → HCID 21991519, compound

HRID 7952Notes

Reaction equation

HRID 7952 reaction equation
C(N1C(=O)C(COS(C)(=O)=O)=CC(C2C=CC(C(F)(F)F)=CC=2)=N1)C(C)C.[C:28]1([C:49]2[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=2)[CH:33]=[CH:32][C:31]([C:34]2[CH:35]=[C:36]([C:45]([O:47]C)=[O:46])[C:37](=[O:44])[N:38]([CH2:40][CH:41]([CH3:43])[CH3:42])[N:39]=2)=[CH:30][CH:29]=1>>[C:28]1([C:49]2[CH:50]=[CH:51][CH:52]=[CH:53][CH:54]=2)[CH:29]=[CH:30][C:31]([C:34]2[CH:35]=[C:36]([C:45]([OH:47])=[O:46])[C:37](=[O:44])[N:38]([CH2:40][CH:41]([CH3:43])[CH3:42])[N:39]=2)=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 21991423HCID 21991423, compoundHCID 219915502-isobutyl-4-methanesulfonyloxymethyl-6-(4-trifluoromet hylphenyl)-2H-pyridazin-3-one

Product 1

HCID 21991519HCID 21991519, compoundYield 79.2%

Procedure

Following the procedure of Example 1 (7), 6-(4-biphenylyl)-2-isobutyl-4-methoxycarbonyl-2H-pyridazin-3-one was reacted to yield the title compound as a colorless crystalline powder (yield: 79.2%).

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-5547f5b907224c35ac7a447e8c6a6065
Source dataset
uspto-grants-2006_08
Patent number
US07087606B2

Reaction notes

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